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This review will outline the multilevel effects of biological sex on HIV acquisition, pathogenesis, treatment response, and prospects for cure. Potential mechanisms will be discussed along with future research directions. HIV acquisition risk is modified by sex hormones and the vaginal microbiome, with the latter acting through both inflammation and local metabolism of pre-exposure prophylaxis drugs. Female sex associates with enhanced risk for non-AIDS morbidities including cardiovascular and cerebrovascular disease, suggesting different inflammatory profiles in men and women.
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NCBI Bookshelf. Center for Substance Abuse Treatment. Early in the U. Early cases of HIV infection that were sexually transmitted often were related to the use of alcohol and other substances, and the majority of these cases occurred in urban, educated, white MSMs. Currently, injection drug users represent the largest HIV-infected substance-abusing population in the United States. The virus is transmitted primarily through the exchange of blood using needles, syringes, or other IDU equipment e. Lack of knowledge about safer needle use techniques and the lack of alternatives to needle sharing e.
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When you are first diagnosed with HIV, you may not want to think about having sex. Some people may be afraid of infecting a partner and decide sex is too risky. These are common reactions, especially if you got HIV through sex. Chances are, however, that you will want to have sex again.
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Watch fullscreen. HIV-positive German singer 'sorry' for unprotected sex. Al Jazeera English. Nadja Benaissa, a member of the German girl band No Angels, has admitted to having unprotected sex despite knowing she was HIV-positive.
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